Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer
Abstract Both TP53 and ESR1 mutations occur frequently in estrogen receptor positive (ER+) metastatic amina muaddi scarpe trasparenti breast cancers (MBC) and their distinct roles in breast cancer tumorigenesis and progression are well appreciated.Recent clinical studies discovered mutual exclusivity between TP53 and ESR1 mutations in metastatic br